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Magnolia is a plant. People use the bark and flower buds to make medicine.
Magnolia is used for weight loss, problems with digestion, constipation, inflammation, anxiety, stress, depression, fever, headache, stroke, and asthma.
Magnolia flower bud is used for stuffy nose, runny nose, common cold, sinus pain, hay fever, headache, and facial dark spots.
Some people apply magnolia flower bud directly to the gums for toothaches.
In rub-on skin care products, magnolia flower bud extract is used as a skin whitener and to minimize or counteract skin irritation caused by the other ingredients.
In traditional Chinese and Japanese (Kampo) medicine, magnolia bark is an ingredient in Hange-koboku-to, which is composed of 5 plant extracts, and in Saiboku-to, which is composed of 10 plant extracts. These extracts are used to decrease anxiety and nervous tension and to improve sleep. Some researchers believe honokiol, a chemical in magnolia bark, is what makes these medicines work.
How does it work?
Magnolia seems to have anxiety-reducing activity in animals. It might also increase steroid production by the body to treat asthma. All research on magnolia has been in laboratories.
QUESTION
Next to red peppers, you can get the most vitamin C from ________________. See AnswerInsufficient Evidence to Rate Effectiveness for...
- Weight loss. So far, there isn't much evidence that magnolia causes weight loss. There is some research showing that overweight women who take a specific product containing a combination of extracts of magnolia plus phellodendron (Relora, Next Pharmaceuticals) don't gain as much weight as other women. They seem to eat fewer calories, possibly because the magnolia reduces their stress-related eating. However, there is no reliable evidence that taking this product actually causes weight loss.
Some other weight loss products include magnolia bark with claims that it reduces cortisol levels. However, there is no evidence that magnolia bark causes weight loss or reduces cortisol levels. In fact, it appears to increase levels of corticosterone, a chemical similar to cortisol. - Anxiety.
- Depression.
- Obesity.
- Digestion problems.
- Inflammation.
- Nasal congestion.
- Runny nose.
- Common cold.
- Headache.
- Facial dark spots.
- Toothaches.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Magnolia is POSSIBLY SAFE for most people when used short-term. The safety of magnolia use for more than 6 weeks is unknown. In one study, one person experienced heartburn, shaking hands, sexual problems, and thyroid problems. Another person experienced extreme tiredness and headache. But it is not known if these side effects were caused by magnolia or some other factor.
Not enough is known to rate the safety of magnolia when applied to the skin.
SLIDESHOW
Vitamin D Deficiency: How Much Vitamin D Is Enough? See SlideshowNot enough is known about the safety of using magnolia during breast-feeding. Stay on the safe side and avoid use.
Surgery: Magnolia can slow down the central nervous system. There is a concern that it might slow down the nervous system too much when combined with anesthesia and other medications used during and after surgery. Magnolia might also slow blood clotting and cause bleeding during and after surgery. Stop using magnolia at least 2 weeks before a scheduled surgery.
AlcoholInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Alcohol can cause sleepiness and drowsiness. Magnolia bark might also cause sleepiness and drowsiness. Taking large amounts of magnolia bark along with alcohol might cause too much sleepiness.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Magnolia might slow blood clotting. Taking magnolia along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Sedative medications (Barbiturates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Magnolia bark might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking magnolia bark along with sedative medications might cause too much sleepiness.
Some sedative medications include amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), and others.
Sedative medications (Benzodiazepines)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Magnolia bark might cause sleepiness and drowsiness. Drugs that cause sleepiness and drowsiness are called sedative medications. Taking magnolia bark along with sedative medications might cause too much sleepiness. Do not take magnolia bark if you are taking sedative medications.
Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.
Sedative medications (CNS depressants)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Magnolia bark might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking magnolia bark along with sedative medications might cause too much sleepiness.
Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.
The appropriate dose of magnolia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for magnolia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4. View abstract.
Hou YC, Chao PD, Chen SY. Honokiol and magnolol increased hippocampal acetylcholine release in freely-moving rats. Am J Chin Med 2000;28:379-84. View abstract.
Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11. View abstract.
Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. View abstract.
Kuribara H, Kishi E, Maruyama Y. Does dihydrohonokiol, a potent anxiolytic compound, result in the development of benzodiazepine-like side effects? J Pharm Pharmacol 2000;52:1017-22. View abstract.
Maruyama Y, Kuribara H, Kishi E, et al. Confirmation of the anxiolytic-like effect of dihydrohonokiol following behavioural and biochemical assessments. J Pharm Pharmacol 2001;53:721-5. View abstract.
Nakazawa T, Yasuda T, Ohsawa K. Metabolites of orally administered Magnolia officinalis extract in rats and man and its antidepressant-like effects in mice. J Pharm Pharmacol 2003;55:1583-91. View abstract.
Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. View abstract.
Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. View abstract.
Wang SM, Lee LJ, Huang YT, et al. Magnolol stimulates steroidogenesis in rat adrenal cells. Br J Pharmacol 2000;131:1172-8. View abstract.
Zhong WB, Wang CY, Ho KJ, et al. Magnolol induces apoptosis in human leukemia cells via cytochrome c release and caspase activation. Anticancer Drugs 2003;14:211-7. View abstract.