Hyssop

Last Editorial Review: 6/11/2021
Other Name(s):

Herbe de Joseph, Herbe Sacrée, Herbe Sainte, Hiope, Hisopo, Hissopo, Hyssopus officinalis, Hysope, Hysope Officinale, Jufa, Rabo De Gato, Ysop.

Overview

Hyssop is a plant. The parts that grow above ground are used to make medicine.

Hyssop is used for digestive and intestinal problems including liver and gallbladder conditions, intestinal pain, intestinal gas, colic, and loss of appetite. It is also used for respiratory problems including coughs, the common cold, respiratory infections, sore throat, and asthma.

Other uses include urinary tract infection (UTI), poor circulation, HIV/AIDS, and menstrual cramps.

Some people use hyssop as a gargle; in baths to cause sweating; and on the skin for treating skin irritations, burns, bruises, and frostbite.

In foods, hyssop oil and extract are used as a flavoring.

In manufacturing, hyssop oil is used as a fragrance in soaps and cosmetics.

How does it work?

The chemicals in hyssop may affect the heart and may increase secretions in the lungs.

QUESTION

Next to red peppers, you can get the most vitamin C from ________________. See Answer

Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

More evidence is needed to rate the effectiveness of hyssop for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Hyssop is considered safe for most people in the amounts commonly found in foods and in medicinal amounts. However, do not use the oil product because it has caused seizures in some people.

SLIDESHOW

Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

Special Precautions & Warnings

Pregnancy and breast-feeding: It is UNSAFE to use hyssop during pregnancy because it might cause the uterus to contract or start menstruation. These effects could lead to a miscarriage.

It's not known whether hyssop is safe to use during breast-feeding. Stay on the safe side and avoid use.

Children: It's UNSAFE to give hyssop to children. Convulsions were reported in a child who took 2-3 drops of hyssop oil over several days.

Seizures: If you have a history of having seizures, don't use hyssop. It might trigger seizures or make them worse.

Dosing

The appropriate dose of hyssop depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for hyssop. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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References

Baek, J. H., Lee, Y. S., Kang, C. M., Kim, J. A., Kwon, K. S., Son, H. C., and Kim, K. W. Intracellular Ca2+ release mediates ursolic acid-induced apoptosis in human leukemic HL-60 cells. Int J Cancer 11-27-1997;73(5):725-728. View abstract.

Brown, D. Encyclopedia of Herbs and Their Uses. 1995.

Cesarone, M. R., Belcaro, G., Pellegrini, L., Ledda, A., Di Renzo, A., Vinciguerra, G., Ricci, A., Gizzi, G., Ippolito, E., Fano, F., Dugall, M., Acerbi, G., and Cacchio, M. HR, 0-(beta-hydroxyethyl)-rutosides, in comparison with diosmin+hesperidin in chronic venous insufficiency and venous microangiopathy: an independent, prospective, comparative registry study. Angiology 2005;56(1):1-8. View abstract.

Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. [Clinical study on treatment of mid-advanced crescentic nephritis by qingre huoxue recipe]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2004;24(12):1084-1086. View abstract.

Es-saady, D., Simon, A., Ollier, M., Maurizis, J. C., Chulia, A. J., and Delage, C. Inhibitory effect of ursolic acid on B16 proliferation through cell cycle arrest. Cancer Lett. 9-10-1996;106(2):193-197. View abstract.

Gollapudi, S., Sharma, H. A., Aggarwal, S., Byers, L. D., Ensley, H. E., and Gupta, S. Isolation of a previously unidentified polysaccharide (MAR-10) from Hyssop officinalis that exhibits strong activity against human immunodeficiency virus type 1. Biochem.Biophys.Res.Commun. 5-5-1995;210(1):145-151. View abstract.

Jantet, G. RELIEF study: first consolidated European data. Reflux assEssment and quaLity of lIfe improvement with micronized Flavonoids. Angiology 2000;51(1):31-37. View abstract.

Jie, L. Pharmacology of oleanolic acid and ursolic acid. Journal of Ethnopharmacology 1-2-1995;49(2-1):57-68.

Keenoy, B., Vertommen, J., and De, Leeuw, I. The effect of flavonoid treatment on the glycation and antioxidant status in Type 1 diabetic patients. Diabetes Nutr Metab 1999;12(4):256-263. View abstract.

Kreis, W., Kaplan, M. H., Freeman, J., Sun, D. K., and Sarin, P. S. Inhibition of HIV replication by Hyssop officinalis extracts. Antiviral Res. 1990;14(6):323-337. View abstract.

Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals.

Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. View abstract.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.

Manufacturer: Nature's Answer. Hanppange, NY.

Manufacturer: Nature's Way. Springville, UT.

Millet Y, Jouglard J, Steinmetz MD, et al. Toxicity of some essential plant oils. Clinical and experimental study. Clin Toxicol 1981;18:1485-98. View abstract.