Cnidium

Last Editorial Review: 6/11/2021
Other Name(s):

Cnidii Monnieri Fructus, Cnidii Rhizoma, Cnidium Extract, Cnidium Fruit, Cnidium Fruit Extract, Cnidium Monnier, Cnidium monnieri, Cnidium Monnieri Fructus, Cnidium Seeds, Extrait de Cnidium, Extrait de Fruit de Cnidium, Fruit de Cnidium, Graines de Cnidium, Monnier's Snowparsley, Selinum monnieri, She Chuang, She Chuang Dze, She Chuang Zi.

Overview

Cnidium is a plant that is native to China. It has also been found in the US in Oregon. The fruit, seed, and other plant parts are used as medicine.

Cnidium has been used in Traditional Chinese Medicine (TCM) for thousands of years, often for skin conditions. It's not surprising that cnidium is a common ingredient in Chinese lotions, creams, and ointments.

People take cnidium by mouth for increasing sexual performance and sex drive, and for treating erectile dysfunction (ED). Cnidium is also used for difficulty having children (infertility), bodybuilding, cancer, weak bones (osteoporosis), and fungal and bacterial infections. Some people also take it to increase energy.

Cnidium is applied directly to the skin for itchiness, rashes, eczema, and ringworm.

How does it work?

Chemicals in cnidium might decrease itching.

QUESTION

Next to red peppers, you can get the most vitamin C from ________________. See Answer

Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

More evidence is needed to rate the effectiveness of cnidium for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

There is not enough information about cnidium to know if it is safe.

SLIDESHOW

Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

Special Precautions & Warnings

Pregnancy and breast-feeding: Not enough is known about the use of cnidium during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Dosing

The appropriate dose of cnidium depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for cnidium. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

References

Cai JN, Basnet P, Wang ZT, Komatsu K, Xu LS, Tani T. Coumarins from the fruits of Cnidium monnieri. J Nat Prod 2000;63:485-8.. View abstract.

Chiou WF, Huang YL, Chen CF, Chen CC. Vasorelaxing effect of coumarins from Cnidium monnieri on rabbit corpus cavernosum. Planta Med 2001;67:282-4.. View abstract.

Kitajima J, Ishikawa T, Aoki Y. Glucides of Cnidium monnieri fruit. Phytochemistry 2001;58:641-4.. View abstract.

Matsuda H, Ido Y, Hirata A, et al. Antipruritic effect of Cnidii Monnieri Fructus (fruits of Cnidium monnieri CUSSON). Biol Pharm Bull 2002;25:260-3. View abstract.

Matsuda H, Tomohiro N, Ido Y, Kubo M. Anti-allergic effects of cnidii monnieri fructus (dried fruits of Cnidium monnieri) and its major component, osthol. Biol Pharm Bull 2002;25:809-12. View abstract.

Meng F, Xiong Z, Sun Y, Li F. Coumarins from Cnidium monnieri (L.) and their proliferation stimulating activity on osteoblast-like UMR106 cells. Pharmazie 2004;59:643-5.. View abstract.

Oh H, Kim JS, Song EK, et al. Sesquiterpenes with hepatoprotective activity from Cnidium monnieri on tacrine-induced cytotoxicity in Hep G2 cells. Planta Med 2002;68:748-9. View abstract.

Tohda C, Kakihara Y, Komatsu K, Kuraishi Y. Inhibitory effects of methanol extracts of herbal medicines on substance P-induced itch-scratch response. Biol Pharm Bull 2000;23:599-601. View abstract.

Yang LL, Wang MC, Chen LG, Wang CC. Cytotoxic activity of coumarins from the fruits of Cnidium monnieri on leukemia cell lines. Planta Med 2003;69:1091-5. View abstract.