Chlorophyllin

Last Editorial Review: 6/11/2021
Other Name(s):

Chlorophylline, Chlorophylline de Cuivre Sodique, Chlorophylline de Sodium et Cuivre, Clorofilina, Sel Cuprique de la Chlorophylle, Sodium Copper Chlorophyll, Sodium Copper Chlorophyllin.

Overview

Chlorophyllin is a chemical that is made from chlorophyll. People use it as a medicine.

Older people take chlorophyllin for controlling body, fecal, and urine odors; and for treating constipation and gas (flatulence).

Don't confuse chlorophyllin with chlorophyll.

How does it work?

There isn't enough information available to know how chlorophyllin works.

QUESTION

Next to red peppers, you can get the most vitamin C from ________________. See Answer

Uses & Effectiveness

Possibly Ineffective for...

  • Controlling urine odor in older patients who can't hold their urine and have a catheter.

Insufficient Evidence to Rate Effectiveness for...

  • Reducing body odors. There is some evidence that chlorophyllin might help reduce body odors in older people.
  • Constipation. Some research suggests that taking chlorophyllin might relieve constipation in older people.
  • Reducing fecal odors. There is some evidence that chlorophyllin might help reduce fecal odors in older people.
  • Gas (flatulence). Some research suggests that taking chlorophyllin might reduce gas in older people.
  • Other conditions.
More evidence is needed to rate the effectiveness of chlorophyllin for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Chlorophyllin seems to be safe for most people.

SLIDESHOW

Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

Special Precautions & Warnings

Pregnancy and breast-feeding: Not enough is known about the use of chlorophyllin during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Dosing

The appropriate dose of chlorophyllin depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for chlorophyllin. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

References

Amara-Mokrane YA, Lehucher-Michel MP, Balansard G, et al. Protective effects of alpha-hederin, chlorophyllin and ascorbic acid towards the induction of micronuclei by doxorubicin in cultured human lymphocytes. Mutagenesis 1996;11:161-7. View abstract.

Dashwood RH, Breinholt V, Bailey GS. Chemopreventive properties of chlorophyllin: Inhibition of aflatoxin B1 (AFB1)-DNA binding in vivo and anti-mutagenic activity against AFB1 and two heterocyclic amines in the Salmonella mutagenicity assay. Carcinogenesis 1991;12:939-42. View abstract.

Nahata MC, Slencsak CA, Kamp J. Effect of chlorophyllin on urinary odor in incontinent geriatric patients. Drug Intell Clin Pharm 1983;17:732-4. View abstract.

Sarkar D, Sharma A, Talukder G. Clastogenic activity of pure chlorophyll and anticlastogenic effects of equivalent amounts of crude extract of Indian spinach leaf and chlorophyllin following dietary supplementation to mice. Environ Mol Mutagen 1996;28:121-6. View abstract.

Wu ZL, Chen JK, Ong T, et al. Antitransforming activity of chlorophyllin against selected carcinogens and complex mixtures. Teratog Carcinog Mutagen 1994;14:75-81. View abstract.

Young RW, Beregi JS Jr. Use of chlorophyllin in the care of geriatric patients. J Am Geriatr Soc 1980;28:46-7. View abstract.