California Poppy

Last Editorial Review: 6/11/2021
Other Name(s):

Amapola de California, Eschscholzia californica, Pavot d'Amérique, Pavot d'Or, Pavot de Californie, Poppy California, Yellow Poppy.

Overview

California poppy is a plant. It is the state flower of California. People use the parts that grow above the ground for medicine.

California poppy is used for trouble sleeping (insomnia), aches, nervous agitation, bed-wetting in children, and diseases of the bladder and liver. It is also used to promote relaxation.

In combination with other herbs, California poppy is used for depression, long-term mental and physical tiredness (neurasthenia), nerve pain, various psychiatric conditions, blood vessel problems, sensitivity to weather changes, and sedation. An herb combination including California poppy is also used for sleep and mood disturbance associated with strong, warm wind in the Alps (foehn illness).

How does it work?

California poppy contains chemicals that might cause relaxation and sleepiness.

QUESTION

Next to red peppers, you can get the most vitamin C from ________________. See Answer

Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

  • Anxiety. Developing research suggests California poppy, in combination with magnesium and hawthorn, might be useful in treating mild-to-moderate anxiety disorders. This combination product, called Sympathyl, is not available in the US.
  • Trouble sleeping (insomnia).
  • Aches.
  • Bed-wetting.
  • Diseases of the bladder.
  • Diseases of the liver.
  • Other conditions.
More evidence is needed to rate the effectiveness of California poppy for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

California poppy appears to be safe for most people when taken appropriately by mouth for three months or less. There isn't enough information to know if California poppy is safe for longer term use.

SLIDESHOW

Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

Special Precautions & Warnings

Pregnancy and breast-feeding: Not enough is known about the use of California poppy during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Surgery: California poppy can slow down the central nervous system, causing sleepiness and other effects. There is some concern that California poppy might slow down the central nervous system too much when combined with anesthesia and other medications used during and after surgery. Stop using California poppy at least 2 weeks before a scheduled surgery.

Interactions


Sedative medications (Benzodiazepines)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

California poppy might cause sleepiness and drowsiness. Drugs that cause sleepiness and drowsiness are called sedatives. Taking California poppy along with sedative medications might cause too much sleepiness.

Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.


Sedative medications (CNS depressants)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

California poppy might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking California poppy along with sedative medications might cause too much sleepiness.

Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

Dosing

The appropriate dose of California poppy depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for California poppy. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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References

Gafner, S., Dietz, B. M., McPhail, K. L., Scott, I. M., Glinski, J. A., Russell, F. E., McCollom, M. M., Budzinski, J. W., Foster, B. C., Bergeron, C., Rhyu, M. R., and Bolton, J. L. Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. J Nat Prod. 2006;69(3):432-435. View abstract.

Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders. Curr Med Res Opin 2004;20:63-71. View abstract.

Paul LD, Maurer HH. Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003;789:43-57. View abstract.

Paul LD, Springer D, Staack RF, et al. Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. Eur J Pharmacol 2004;485:69-79. View abstract.

Rolland A, Fleurentin J, Lanhers MC, et al. Behavioural effects of the American traditional plant Eschscholzia californica: sedative and anxiolytic properties. Planta Med 1991;57:212-6. View abstract.

Rolland A, Fleurentin J, Lanhers MC, et al. Neurophysiological effects of an extract of Eschscholzia californica Cham. (Papaveraceae). Phytother Res 2001;15:377-81. View abstract.