What Is the Most Effective Antibiotic for UTI?

The vast majority of UTIs are caused by Escherichia coli (E. coli), a bacteria usually found in the digestive system. Chlamydia and mycoplasma bacteria can infect the urethra but not the bladder. UTIs occur when these microbes enter your kidneys, ureters, urinary bladder and urethra. 

People of any age and sex can develop UTIs. However, UTI is very common in teens and young women because the female urethra is shorter and closer to the anus.

Types of UTIs include:

• Lower tract infections: These involve the urethra and urinary bladder (cystitis). Bacteria in the intestine is the main cause of lower UTIs. The bacteria spread from the anus to the urethra and bladder, where they grow, invade the tissue and cause infection.
• Upper tract infections: These involve the ureters and kidneys (pyelonephritis) and require hospitalization. Upper UTIs usually occur when bacteria travel up from the bladder into the kidneys. Sometimes, they occur when bacteria travel from other areas of the body through the bloodstream and settle in the kidneys. This is common in the elderly, people with diabetes and those with poor immunity.

Factors that increase the likelihood of developing UTIs include:

• Sexual intercourse, especially if more frequent, intense and with multiple or new partners
• Diabetes mellitus
• Poor personal hygiene
• Problems emptying the bladder completely
• Having a urinary catheter
• Bowel incontinence
• Blocked flow of urine
• Kidney stones
• Pregnancy
• Menopause
• Procedures involving the urinary tract
• Suppressed immune system
• Immobility for a long period
• Use of spermicides and tampons
• Heavy use of antibiotics, which can disrupt the natural flora of the bowel and urinary tract

Signs and symptoms of UTIs vary depending on age, gender and what part of the urinary tract has been infected. Most common signs and symptoms include:

• Strong, persistent urge to urinate
• Frequent, small amounts of urine
• Urine that appears cloudy or frothy
• Urine that appears red, bright pink or cola-colored—a sign of blood in the urine
• Strong-smelling urine
• Burning sensation when urinating
• Pelvic pain (lower back pain) in women

Diagnosis will usually be made after verifying your symptoms and testing your urine sample to assess the presence of white blood cells, red blood cells and bacteria. 

If you have recurrent UTIs, your doctor may request further diagnostic testing to determine the cause. Tests include:

• Diagnostic imaging involves assessing the urinary tract using ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) scans.
• Urodynamics determines how well the urinary tract is storing and releasing urine.
• Cystoscopy allows your doctor to see inside your bladder and urethra with a camera lens, which is inserted through the urethra through a long thin tube.
• Intravenous pyelogram involves injecting a dye into your body that travels through your urinary tract taking an X-ray of your abdomen. The dye highlights your urinary tract on the X-ray image.

Sufficient hydration and suitable oral antibiotics are first-line treatments for urinary tract infections. Home remedies include:

• Consuming cranberry juice, probiotics and vitamin C
• Placing a heating pad on the abdomen to temporarily relieve pain and discomfort

For severe UTIs, the treatment may include intravenous antibiotics in the hospital.

Sexual intercourse introduces bacteria and other microbes from outside the body into the urinary tract. Practicing good sexual hygiene can help reduce the amount of bacteria transferred during sexual activity:

• Urinate after having sex, which can help flush out any bacteria. 
• Avoid diaphragms and spermicide condoms. 
• Avoid scented products near the genital areas, as these can irritate the urethra.